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Michael Hagan hagan@brandeis.edu
Assistant Professor of Physics |
Michael Hagan’s lab endeavors to understand how fundamental physical principles lead to the forces that control assembly and dynamic pattern formation in biological and biomimetic systems. Because assembling structures can be orders of magnitude larger than the individual components, his lab develops and applies computational and theoretical methods that bridge disparate length and time scales. Applications of these methods include understanding assembly mechanisms for viral capsids and other large protein complexes, and learning to direct the rational design of novel materials with biomimetic function.
For further information please visit Michael Hagan’s research page .
Sample of Recent Publications
Hagan, M. F. "Controlling viral capsid assembly with templating" , Phys. Rev. E, 2008, 77, 051904. PDF
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Jack, R.L., M.F. Hagan, and D. Chandler, "Fluctuation-dissipation ratios in the dynamics of self-assembly." Physical Review E, 2007. *76*: in press.
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Hagan, M. F.; Chandler, D. "Dynamic Pathways for Viral Capsid Assembly", Biophysical Journal, 2006. *91*(1): p. 42-54. PDF
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Hagan, M. F.; Chakraborty, A. K. "Hybridization Dynamics of Surface Immobilized DNA", J. Chem. Phys. (2004), 120, 4958. PDF
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Hagan, M. F.; Dinner, A. R.; Chander, D.; Chakraborty, A. K. "Atomistic Understanding of Kinetic Pathways for Single Base-Pair Binding and Unbinding in DNA", PNAS (USA) (2003), 100, 13922. PDF
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Hagan, M. F.; Majumdar, A.; Chakraborty, A. K. "Nanomechanical Forces Generated by Surface Grafted DNA", J. Phys. Chem. B (2002), 106, 10163. PDF
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Wu, G.; Haifeng, J.; Hansen, K.; Thundat, T.; Datar, R.; Cote, R.; Hagan, M. F.; Chakraborty, A. K.; Majumdar, A. "Origin of Nanomechanical Cantilever Motion Generated from Biomolecular Interactions",PNAS (USA) (2001), 98, 1560. PDF