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Seth Fraden fraden@brandeis.edu Professor of Physics |
The focus of Seth Fraden and his group is to understand the relation between interparticle interactions and phase transitions in colloidal suspensions such as genetically engineered viruses, latex, proteins, and polymers. Combining experiment, computer simulation, and theory, Fraden examines the role of entropy in driving disorder-to-order transitions. Other major objectives are to understand the physics of protein crystallization and the development of microfluidic based high throughput crystallization devices.
Recent Ph.D. Students:
Jung-uk Shim (2007) “ Novel Approach to Protein Crystallization; Control of the Phase Behavior of Aqueous Solutions Using Microfluidics.”
Present Position: Samsung Electronics Co. LTD, Seoul, South Korea
Joshua Bloustine (2006) “Experimental Investigations of Interactions and Collective Behavior in Protein/Polymer Mixtures and Granular Rods” Present Position: Postdoctoral Research Associate, Institut de Science et d Ingénierie Supramoléculaires, Strasborg, France
Kirstin R. Purdey (2004) “Liquid Crystal Phase Transitions of Mono- disperse and Bidisperse Suspensions of Rodlike Colloidal Virus” Present Position: Postdoctoral Fellow, University of Illinois, Urbana-Champaign Dept of Materials Science and Engineering, Urbana, IL
Sample of Recent Publications:
Soft Matter, vol. 2: Complex Colloidal Suspensions, Gompper, G / Schick, M (eds.), Chap. 1: Phase Behavior of Rod-Like Viruses and Virus-Sphere Mixtures, Z. Dogic and S. Fraden, 1st ed., Wiley-VCH, Weinheim, 2005.
Ordered phases of filamentous viruses. Z. Dogic and S. Fraden, Current Opinion in Colloid & Interface Science 11, 47 - 55 (2006).
Light scattering and phase behavior of Lysozyme-PEG mixtures. J. Bloustine, T. Virmani, G. M. Thurston, and S. Fraden. Phys. Rev. Lett. 96, 087803 (2006).
Nematic-nematic phase separation in binary mixtures of thick and thin hard rods:
Results from Onsager-like theories. S. Varga, K. Purdy, A. Galindo, S. Fraden, and G. Jackson. Phys Rev E 72, 051704 (2005).
Nematic Phase transitions in Mixtures of Thin and Thick Colloidal Rods. K. R. Purdy, S. Varga, A. Galindo, G. Jackson, and S. Fraden. Phys. Rev. Lett. 94, 057801 (2005).
Isotropic-cholesteric phase transition of filamentous virus suspensions as a function of rod length and charge. K. R. Purdy and S. Fraden. Phys. Rev. E 70, 061703 (2004).
Isotropic-Nematic phase transition in suspensions of filamentous virus and the neutral polymer Dextran. Z. Dogic, K. Purdy, E. Grelet, M. Adams, and S. Fraden. Phys. Rev. E 69, 051702 (2004).
Our lab mentioned in Science News, Vol. 164, No. 1, July 5, 2003, p. 7.
Microbial Materials: Scientists co-opt viruses, bacteria, and fungi to build new structures
Measurements of Protein-Protein Interactions by Size Exclusion Chromatography J. Bloustine, V. Berejnov and S. Fraden, Biophysical Journal 85: 2619-2623 (2003).
What is the origin of chirality in the cholesteric phase of virus suspensions? E. Grelet and S. Fraden. Phys. Rev. Lett. 90, 198302 (2003).
Measuring the nematic order of colloidal fd virus by x-ray diffraction K. Purdy, Z. Dogic, S. Fraden. A. Ruehm, L. Lurio, and S. G. J. Mochrie. Phys. Rev. E. 67 031708 (2003).